Neurological symptoms in COVID-19 patients

OBJECTIVES: Our study aimed to investigate neurological symptoms in patients with COVID-19 and contribute this area of limited knowledge. BACKGROUND: Increasing evidence shows that neurotropism is a common feature Coronaviruses (CoVs). Like the other CoVs, SARS-CoV 2 uses angiotensin-converting enzyme (ACE2). The brain thought express ACE2 receptors detected on glial cells neurons. There are also skeletal muscles. METHODS: A total 51 patients, presented hospitalized our hospital between March 23, 2020 April 16, were included study. diagnosis all was made according WHO interim guideline. divided into two subgroups as mild severe course severity disease. RESULTS: Neurological 16 (31.37 %) patients. Muscle injury 10 (19.61 most symptom headache (n: 9, 17.65 %). When frequency compared those disease, no significant differences found groups. muscular involvement course, CONCLUSION: nervous system muscle may be among viral targets. Detection some findings valuable predicting Some laboratory values can allow disease (Tab. 5, Ref. 23) Keywords: COVID-19, neurotropism, injury, headache.